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A deficiency can lead to megaloblastic anaemia, a condition that causes symptoms like weakness and fatigue

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Its levels decline with age, and research focuses on wound healing, collagen synthesis, and anti-inflammatory pathways

However, blinded adjudication of the above studies 192 revealed that osteonecrosis was not primary in these cases, but tanezumab treatment was associated with an increase in the rapid progression of osteoarthritis

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